Hanchen Wang    |  Publication  |  Misc  |  Bio  |
wang.hanchen at gene.com  |  hanchenw at cs.stanford.edu
My first-author papers (Nature, NeurIPS etc.) are highlighted by 1000+ tweets, 50+ press including:
A new series in Nature on "AI for Science", DeepMind, The Economist, Harvard Medical School, Chemical & Engineering News, Tech Crunch, Yahoo! News, a few Wikipedia pages, Tech Xplore, University of Cambridge, healthcare-in-europe.

Besides AI/ML, I'm trained and have published in Physics (my foundation and childhood's favorite, High School Olympiad), Biology (wild learner, also High School Olympiad), Chemistry / Materials / Electronics, Medical Science, and Clinical Trials :)

Postdoc, in Novel Therapeutics & AI for Science, Aug 2023-26

Along my postdoc fellowship, I'm excited about the potentials of single cell genomics and AI in developing novel therapeutics. I'm exploring the use of frontier AI (e.g., Foundation Model, Generative AI, ML System, Agent), along with biomed frontiers including live cell imaging, organoid systems, lab-in-the-loop paradigms, AAV & LNP deliveries. Also, I'm working on data centric methods that aim to benefit many sciences. I believe AI will revolutionize the way we do science and treat cancer.

Metric Mirages in Cell Embeddings
Hanchen Wang, Jure Leskovec#, Aviv Regev#
in submission

PhD, in Machine Learning, Oct 2019-22

Doctoral Thesis: Learning from Structured Data with Weak Supervision

During my three-year PhD (with full fellowship), I shifted to AI, published my 1st paper till the end of my 2nd year (ICCV '21). I have been working on data including votes from polls, point clouds, CT/CXR scans, histological and pathological images, molecular and relational graphs, as well as single-cell transcriptomics. I develop methods that can learn structures from these data with weak supervisions. Aside from this, I spent some time on quantum computation also did four interns in tech and biotech industries (Google -> Amazon -> BioMap -> Iambic). Back in 2018, I co-founded a startup (as the CTO) with Stanford and Berkeley alumni, aimed at transforming electronic health records via language models, with partnerships among 37 hospitals. Though things didn't work out then, my commitment to harnessing AI's power in Healthcare remains steadfast.
Last batch of works are near completion, including a new cell atlas, a llm for maths, a clinical trial, a robotics lab demo.
Deciphering Batch Effects with Concept Bottlenecks
Hanchen Wang*, et al., Chao Tang#, John Marioni#
in submission
Long-lived TIL Phenotypes Delineate Clinical Response to Liver Cancer with Adoptive Cell Therapy
Lijun Chen et al., Tian Xia#
Pivot Trial, now in IND Phase
in revision, Cell
Machine Learning Systems: Design and Implementation
Tsinghua University Press 2023, Table of Contents
also in press, Springer Nature
Scientific Discovery in the Age of AI
Hanchen Wang* et al., Connor Coley, Yoshua Bengio, Marinka Zitnik# [Team] >
Nature 2023
Focalizing Regions of Relevance Facilitates Biomarker Prediction on Histopathological Images
Jiefeng Gan*, Hanchen Wang*, Hui Yu*, et al., Tian Xia#
iScience 2023
Evaluating Self-supervised Learning for Molecular Graph Embeddings
Hanchen Wang*, Jean Kaddour*, Shengchao Liu, Jian Tang, Joan Lasenby, Qi Liu
NeurIPS 2023, Datasets and Benchmarks Track
GraphCG: Unsupervised Discovery of Steerable Factors in Graphs
Shengchao Liu et al.,
TMLR 2024
Augmenting Message Passing by Retrieving Similar Graphs
Dingmin Wang et al.,
ECAI 2023
Pre-training Molecular Graph Representation with 3D Geometry
Shengchao Liu, Hanchen Wang, Weiyang Liu, Joan Lasenby, Hongyu Guo, Jian Tang
ICLR 2022
Matching Point Sets with Quantum Circuits Learning
Hanchen Wang*, M. N.* (in contribution order)
ICASSP 2022, Invited by Editors, with Travel Award
Graph Denoising with Edge Editing
Hanchen Wang, Yunlong Jiao, Jordan Massiah
contributed talk at Amazon Machine Learning Conference 2021
Advancing COVID-19 Diagnosis with Privacy-Preserving Collaboration in Artificial Intelligence
Xiang Bai (Prof.)* Hanchen Wang*, Liya Ma*, Yongchao Xu*, Jiefeng Gan*, ..., Carola Schönlieb#, Tian Xia#
Nature Machine Intelligence 2021
Iterative Teaching by Label Synthesis
Weiyang Liu*, Zhen Liu*, Hanchen Wang*, Liam Paul, Bernhard Schölkopf, Adrian Weller
NeurIPS 2021, Spotlight
Neural Random Subspace
Yun-Hao Cao, et al.,
Pattern Recognition 2021
Unsupervised Point Cloud Pre-training via Occlusion Completion
Hanchen Wang, Qi Liu, Xiangyu Yue, Joan Lasenby, Matthew J. Kusner
ICCV 2021
An Empirical Study on Learning Fairness Metrics for COMPAS Data with Human Supervision
Hanchen Wang, Nina Grgić-Hlača, Preethi Lahoti, Krishna. P. Gummadi, Adrian. V. Weller
axXiv, presented at NeurIPS HCML 2019, with Travel Award

Undergraduate, in Physics, Sep 2014-18

In addition to studying Theoretical Physics, I researched next-gen electronic devices such as transistors and solar cells, a field at the nexus of Solid-State Physics, Material Sciences and Electrical Engineering. I primarily worked in Xinran Wang's and Ali Javey's groups. I also accumulated experience in the finance sector, initially focusing on bonds then transitioning to roles in quantitative trading of equity and crypto. These diverse experiences ultimately cemented my commitment in advancing Science and Engineering with the aim of improving human life. Finance is boring, technology is fun and the future :)
Current-controlled Propagation of Spin Waves in Antiparallel, Coupled Domains
Nature Nanotechnology 2019
Dopant‐Free Partial Rear Contacts Enabling 23% Silicon Solar Cells
Advanced Energy Materials 2019
Stable dopant-free asymmetric heterocontact silicon solar cells with efficiencies above 20%
ACS Energy Letters 2018
Negative Capacitance 2D MoS2 Transistors with Sub-60mV/dec Subthreshold Swing over 6 Orders, 250 μA/μm Current Density, and Nearly-Hysteresis-Free
Zhihao Yu*, Hanchen Wang* et al., Xinran Wang#
IEDM 2017, Oral, NJU's 1st IEDM. It is where Intel, NVIDIA, TSMC, AMD etc sharing their secret sauce on chip design :)
Molecular Mechanism of Self-Assembly of Aromatic Oligoamides into Interlocked Double-Helix Foldamers
Journal of Physical Chemistry B 2017
Microchannel contacting of crystalline silicon solar cells
Scientific Reports 2017
Logical integration device for two-dimensional semiconductor transition metal sulfide
Weisheng Li*, Jian Zhou*, Hanchen Wang* et al., Xinran Wang#
Invited Review, Acta Physica Sinica 2017